UCLA Department of Statistics

2010 Archives

SCC-TR-2010-0005: Neonatal Candidiasis Risk Factors

Mine Çetinkaya

Medical researchers at UCLA Medical Center Pediatric Infectious Diseases Clinic are studying the effect of treatment delay and various other factors in neonatal candidiasis. We conducted logistic regression analysis to determine how treatment delay and other various factors affect the likelihood of survival of the subject. We also investigated the relationship between these factors and the outcome when patients whose only culture was from a respiratory source were excluded from the analysis.

Posted on Nov 15, 2010

SCC-TR-2010-0004: CVCB Antimicrobial Lock Therapy Study

Mine Çetinkaya, Colin Rundel

Medical researchers at Department of Infectious Diseases and Microbiology at the Stamford Hospital in Stamford, CT are studying episodes of central venous catheter-related bacteremia (CVCB) that have become common events in patients with long-term indwelling central venous catheter use. Since no standardized treatment of CVCB exists, novel approaches have been used to salvage infected catheters where vascular access is limited. Use of antibiotic lock solutions (e.g., a solution of an antibiotic agent and heparin) to fill catheter lumens between treatments (antibiotic-lock treatment, ALT) has been shown to prevent CVCB and may be useful for treatment of already-infected catheters. In this report we analyze the success of ALT in preventing CVCB.

Posted on Feb 24, 2010

SCC-TR-2010-0003: Type 2 Diabetes Mellitus and Melatonin Levels

Mine Çetinkaya

Medical researchers at the UCLA Medical Center Endocrinology Clinic are planning a study investigating the melatonin levels of patients with type 2 diabetes mellitus. We provided them with a power analysis in order to help them determine the sample size required for certain effect size and power combinations.

Posted on Feb 24, 2010

SCC-TR-2010-0002: Assersion of comprehensive approach to dermatology

Masanao Yajima

Study was conducted to see if comprehensive approach to dermatology is more effective than treating the skin condition alone with topicasls. Subjects were divided into the treatment and control group and 10 minute educational intervention was given to the treatment group along with topical corticosteroids and just topical corticosteroids and no intervention to the control group. Several kinds of measurements were taken before and after the intervention for the treatment group and control group of which 4 are of primary interest; phase angle, basal metabolic rate, intracellular water, and free fat mass. Result showed treatment effect in the expected direction, yet because of the small sample size result showed that treatment was not statistically significant.

Posted on Aug 20, 2010